Tools and Team

Sensory processing and sensory perception – Visual integration is often thought as a passive, stimulus driven process leading to a reliable representation of the visual scene. We are starting to understand that it is not the case. Sensory processing is dynamically adapted to our perceptual needs. Several neuropsychiatric disorders such as autism and schizophrenia might result from dysfunctions in those adaptation mechanisms. Learn more

Development and maintenance of cortical networks – Determining how neurons connect each others during development is essential for understanding the emergence of complex cerebral functions and behaviors. Moreover, despite the apparent stability of the cortical functions, cortical connectivity is constantly reorganized during adulthood. Several major neurological disorders are associated with the creation of abnormal neuronal connectivity during development and/or failures in maintaining the connectivity during adulthood. Learn more

Epilepsy – Epileptic seizures are events during which cortical neurons present an abnormal highly synchronized activity. We are investigating the mechanisms of epiletogenesis (how epileptic networks are created), the mechanisms of ictogenesis (how seizures start), and the mechanisms by which epileptic seizures propagate in the brain.

Calcium imaging – allows recording hundreds of neurons simultaneously in mice performing a perceptual task.

Two-photon targeted whole cell recordings – allows to understand how neurons integrate sensory information during behavior

Behavioral training – Mice can learn different perceptual tasks that allow us to probe their visual perception